From: https://www.ptcusercommunity.com/thread/116441
atwood May 12, 2010 5:37 AM (in response to PreetiGupta) As long as you pay attention to the ADDM reports and keep the stats job running regularly, you shouldn't need the PTC Tuner package for 10g or 11g. It has become redundant after 9i. Tim Atwood
From: https://www.ptcusercommunity.com/thread/33700
JørnAHansen Jan 25, 2011 9:42 AM (in response to egifford) AFAIK the new "Windchill Application Database User" is a separate user that some organizations might require to increase application security. As I understood this the "Application" user is used by Windchill during normal operation is not allowed to alter the database schema. For a test setup you should be fine just defining the "Windchill Installation Database User Account" and everything will run with this database user as in 9.1.
Introduction to Windchill PDMLink 10.0 Webinar: https://www.youtube.com/watch?v=7_1xuoVYU8c